Joint Synergy (90-Day Supply)
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Joint Synergy
(90-Day Supply)

#360 Veggie Caps (90-Day Supply)

Price: $108.75
Product ID : CBJS
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Cycle-Breakers® Joint Synergy™ is a formula that combines nutritional cartilage support (glucosamine sulfate and chondroitin sulfate) with a natural inhibitor of COX-2 (Boswellia) for optimal joint health.  As this formula was born of research on clinical studies of efficacy, we can’t make a case for this product as well as the abstracts below.  Click on the links to view the full PubMed abstract.

Selected Study Summaries:

Lancet. 2001 Jan 27;357(9252):251-6
Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial.

This randomized, double-blind, placebo controlled study of 212 patients with osteoarthritis on the knee suggests that 1500mg per day of glucosamine sulfate significantly reduces joint degeneration (assessed by joint space narrowing and symptoms) over 3 years, compared to placebo.

Arch Intern Med. 2002 Oct 14;162(18):2113-23
Glucosamine sulfate use and delay of progression of knee osteoarthritis: a 3-year, randomized, placebo-controlled, double-blind study.

This randomized, double-blind, placebo controlled study also suggests that 1500mg per day of glucosamine sulfate may significantly prevent progression of knee osteoarthritis compared to placebo.

Osteoarthritis Cartilage. 2004 Apr;12(4):269-76
Intermittent treatment of knee osteoarthritis with oral chondroitin sulfate: a one-year, randomized, double-blind, multicenter study versus placebo.

This randomized, double-blind, placebo controlled study assessed the effect of an 3 month intermittent treatment using 800mg of chondroitin sulfate on knee osteoarthritis. The study demonstrated that this treatment significantly prevent the progression of knee osteoarthritis (assessed by joint space narrowing on radiographs and pain symptoms).

Drugs Exp Clin Res. 2004;30(1):11-6
A two-year study of chondroitin sulfate in erosive osteoarthritis of the hands: behavior of erosions, osteophytes, pain and hand dysfunction.

This study demonstrated that 800mg/day of chondroitin sulfate over 2 years may prevent the progression of subjective measures of erosive osteoarthritis of the hands, but not impact objective measures of the disease.

J Rheumatol. 2001 Jan;28(1):173-81
Chondroitin sulfate in osteoarthritis of the knee: a prospective, double blind, placebo controlled multicenter clinical study.

This randomized, double-blind, placebo controlled study demonstrated the 1gram/day of chondroitin sulfate significantly alters the course of knee osteoarthritis. The researchers found that the chondroitin sulfate group had better results in functional tests, pain with activity, pain at rest, and physician assessment, compared with placebo.

Biofactors. 2000;13(1-4):225-30
Anti-tumor and anti-carcinogenic activities of triterpenoid, beta-boswellic acid.

This in vivo and in vitro study demonstrates that boswellic acid (from Boswellia) has potent anti-inflammatory among other attributes. The researchers conclude "beta-boswellic acid and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemic activities."

Phytomedicine. 2003 Jan;10(1):3-7
Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee - a randomized double blind placebo controlled trial.

This randomized, double-blind, placebo controlled study demonstrated the boswellia may improve the subjective measures of knee pain, knee flexion, and walking ability as well as the objective measure of knee swelling, in patient with knee osteoarthritis.

Supplement Facts:
Serving Size: 4 capsules
Servings per container: 90
Glucosamine (1,500mg)
Chondroitin Sulfate (BSE Cert) (1,200mg)
Boswellia Extract 60% (250mg)
Other Ingredients: Cellulose (capsule), Magnesium Stearate, Silica.
Recommended Dose: Four capsules per day, preferably divided as two with breakfast and two with dinner, or as directed by your practitioner.

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